Born 1932 in Warri, Alele-Williams took her PhD at the University of Chicago in 1963 with a thesis on the dynamics of curriculum change in West African schools. She joined the University of Ibadan, then moved to the University of Benin, eventually becoming its Vice-Chancellor in 1985 — the first Nigerian woman to head a university.
Her published mathematics-education work, across the *Journal of Research in Mathematics Education*, the *International Journal of Mathematical Education in Science and Technology*, and *Studies in Educational Evaluation*, anchored the African Mathematical Union Commission on Women in Mathematics in Africa (which she chaired) and the Mathematical Association of Nigeria modern-mathematics curriculum project of the 1970s.
She died in 2022. Her career is one of the very few in which a Nigerian university researcher reshaped a school system — the secondary-school mathematics syllabus used across the West African Examinations Council region is substantially a descendant of the modern-mathematics work she led.